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Patients treated with both dosing regimens of ixekizumab had significantly greater levels of skin clearance compared to placebo and to etanercept at the 12-week endpoint. Epidermis licence was quantified through level peerless endpoints for psoriasis studies: the Psoriasis Area and Pitilessness Index (PASI) and the Static Physician Broad Assessment (sPGA).

Representing patients treated with ixekizumab either every four weeks or every two weeks, between 78 to 90 percent of patients achieved at least a 75 percent reduction in PASI her own coin (PASI 75) at 12 weeks. Additionally, 31 to 41 percent of these patients achieved PASI 100, or exonerate husk, at week 12. An eye to similarity, between 5 to 7 percent of patients treated with etanercept in the UNCOVER-2 and 3 studies achieved PASI 100.

Statistically meritorious improvements in pellicle room measures exchange for patients treated with ixekizumab were observed as early as the from the start week when compared to either placebo or etanercept, and continued in the course week 12. In the UNCOVER-1 study, squiffed levels of effect were maintained into done with 60 weeks of treatment.

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